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Read Now: Blue Light Speeds Up Aging? In Flies, Maybe – 101 Latest News

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Blue Light Speeds Up Aging? In Flies, Maybe

#Blue #Light #Speeds #Aging #Flies

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A new study this week suggests that long-term exposure to blue light may not be so harmless, at least for fruit flies. Researchers found that chronic blue light exposure prematurely aged the flies and damaged their brains, likely due to certain metabolic changes. But it’s not known whether blue light could cause similar harm in humans, and the exposure people get from phone screens and indoor lighting isn’t likely to be worse than the blue light naturally present in sunshine.

The research comes from a team of scientists at Oregon State University, who have been studying the effects of blue light on the common fruit fly (Drosophila melanogaster) for several years now. Their past work has indicated that blue light can speed up the aging process in these short-lived insects (in optimal conditions, they live up to 50 days) and even cause neurological damage. In their latest work, published Wednesday in the journal Frontiers in Aging, the team wanted to get a better understanding of why these effects seem to happen.

To do this, they compared two groups of fruit flies: one that had been left under constant blue light for 10 or 14 days, and the other that had been kept in complete darkness instead. They specifically focused on the metabolism of both fly groups, or how the insects broke down nutrients and other molecules for energy. The blue light flies once again showed signs of premature aging and neurodegeneration. And when compared to the control group, the flies also had noticeably different levels of these metabolic byproducts, as well as lower levels of important neurotransmitters.

“Our research, which was performed on fruit flies, suggests that long-time exposure to blue light results in reduced energy production and this is detrimental to cellular health. This conclusion is based on experiments showing that blue light can alter the levels of indispensable metabolites in flies,” senior study author Jadwiga Giebultowicz, a professor at OSU’s Department of Integrative Biology, told Gizmodo in an email.

Blue light is one of the shortest wavelengths of light on the visible spectrum, meaning that it’s relatively high energy. For some time, it’s been suspected that blue light from our phones and other devices as well LED lighting could be harmful to human health, particularly our eyes. These concerns have also led to a sort of cottage industry of products claiming to protect people from the pervasive harms of blue light, such as specialized goggles or skin care products, though not always with great success.

One important factor here is that the most potent source of blue light is actually natural daylight. And many experts believe that if blue light can be harmful to our cells, that harm is likely to come much more from the Sun—which also contains damaging ultraviolet light—than from much weaker artificial sources of blue light.

Animal studies like the current one have shown that high and/or chronic doses of blue light can damage cells, including those in the retina, but research in humans so far hasn’t shown a similar effect from the light we get specifically from our phones.

There is a stronger case for blue light mucking with our bodily clock, since it plays a noticeable role in regulating our production of the hormone melatonin. Too much blue light at night seems to suppress melatonin production, making it harder to fall asleep, and poor sleep can then lead to poor health. Even this hypothesis is controversial, though, with a 2019 study in mice suggesting that any bright light in general, not specifically blue light, can ruin our sleep (the study also suggested that yellow light may actually be worse than blue).

Giebultowicz does note that most people aren’t spending their entire work days out in the Sun, but they are usually sitting under artificial sources of mostly blue light. So it is still possible that our blue light-rich environment in these modern times is having a uniquely negative effect on our health. The team suspects that some of the same damaging metabolic changes they saw in fruit flies exposed to chronic blue light can happen in humans, but Giebultowicz says that these changes could be more subtle.

In any case, it will take more research—particularly in humans—to suss out if and just how bad blue light is for us. For their part, the researchers do plan to keep digging.

“We are investigating the effects of blue light on gene expression in flies and hope to collaborate with other researchers to study the impact of blue light on human cells,” Giebultowicz said.

More: Do You Really Need a Sunscreen With Blue Light Protection?

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Read Now: Best phones under Rs 40,000 (May 2023): OnePlus 11R 5G, Samsung Galaxy S21 FE 5G to iQOO 9 5G – 101 Latest News

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Best phones under Rs 40,000 (May 2023): OnePlus 11R 5G, Samsung Galaxy S21 FE 5G to iQOO 9 5G

#phones #OnePlus #11R #Samsung #Galaxy #S21 #iQOO

There were quite a few handsets vying for a slot on our sub-40K list of phones this month. After much deliberation, we have shortlisted five. This budget gives you access to some premium features like flagship-grade processors, high quality cameras with OIS, excellent high refresh rate displays and more. You get phones suitable for gamers as well as photography enthusiasts in this budget. So let’s take a look at the best options you can get your hands on under Rs 40,000 this May.

Best phones to buy under Rs 40,000 in India

OnePlus 11R 5G
OnePlus had a strong start to the year courtesy of the launch of the OnePlus 11 series. While the flagship OnePlus 11 5G is loaded with more bells and whistles, the more affordable 11R 5G is no pushover either, and borrows a lot of goodness from its more premium sibling including the design. This stylish phone looks just like the 11 5G from the front and back, barring the placement of the front camera and a missing Hasselblad logo at the back.

The OnePlus 11R has a curved display too, measuring 6.74-inch with an unusual (higher than Full HD) resolution of 2772 x 1240 pixels. You get a standard Fluid AMOLED display here instead of the more premium LTPO3 variant on the 11. This HDR10+ compliant screen supports 10-bit colour, 120 Hz refresh rate and can get up to 1450 nits bright. This phone is powered by Qualcomm’s previous generation flagship Snapdragon 8+ Gen 1 chip, and you get its 8 GB RAM and 128 GB UFS 3.1 storage variant in this budget.

The 50MP primary camera with OIS but without Hasselblad’s colour tuning is quite impressive and does most of the heavy lifting. The support cast is modest with an 8MP ultrawide camera and a 2MP macro camera. There’s a 16MP selfie camera too. Its 5000 mAh battery can last for a day and a half of moderate use, and the bundled 100W charger promises to juice it up in just 25 minutes. The phone runs OxygenOS 13 based on Android 13 and one can expect several OS and security updates going forward.

OnePlus 11R 5G price in India: Rs 39,999 for 8GB RAM/128GB storage

Motorola Edge 30 Pro 5G
The Motorola Edge 30 Pro 5G seems to have received further price cuts and you can now get it under 35K. This phone is powered by Qualcomm’s previous flagship Snapdragon 8 Gen 1 chip, which is still extremely powerful, and comes with 8 GB RAM and 128 GB internal storage. Its 6.7-inch Full HD+ OLED screen flaunts a 144 Hz refresh rate, HDR10+ compliance and can display over a billion colours. You get Corning Gorilla Glass protection against scratches at the front and back.

Motorola Edge 30 Pro 5G

The photography department on the Motorola Edge 30 Pro is impressive too, starting with a 50MP primary camera with optical image stabilisation (OIS) and another 50MP camera for ultra-wide photography; there’s a 2MP depth sensor too. The 60MP front camera is bound to impress the selfie crowds. This phone has a 4800 mAh battery that comfortably lasts close to a day and a half of moderate use and supports 68W fast charging as well as 15W fast wireless charging. This phone launched with Android 12, and an Android 13 update has started rolling out. Like most Motorola phones, you get a clean and near-stock user interface.

Motorola Edge 30 Pro 5G price in India: Rs 34,999 for 8GB RAM/128GB storage

Samsung Galaxy S21 FE 5G
The Samsung Galaxy S21 FE 5G is another great option in this budget. This phone has a sleek design and also flaunts an IP68 rating for dust and fluid resistance. It has a 6.4-inch Full HD+ Dynamic AMOLED 2X display with HDR10+ compliance, 120 Hz refresh rate and Corning Gorilla Glass Victus protection. It is powered by Samsung’s Exynos 2100 chip which can be found in several premium phones from the company. You can get its 8 GB RAM and 128 GB internal storage variant in this budget. The phone launched with Android 12, and is upgradeable to Android 13 with Samsung’s One UI 5.

Samsung Galaxy S21 FE 5G

Photography department on the Samsung Galaxy S21 FE 5G consists of three cameras at the back starting with a 12MP primary camera with OIS, a 12MP ultra-wide camera with 123 degrees FOV and an 8MP telephoto camera with OIS that provides 3X optical zoom. The camera performance is impressive with excellent detail and wide dynamic range, and with a strong low light performance too. A 4500 mAh battery keeps the phone running for close to a day and a half of moderate use and supports wireless charging as well.

Samsung Galaxy S21 FE 5G price in India: Rs 39,999 for 8GB RAM/128GB storage

iQOO 9 5G
The iQOO 9 5G is for those looking for a solid camera phone with ample storage under 40K. It is powered by Qualcomm’s earlier flagship Snapdragon 888+ chip, and you get its 12 GB RAM and 256 GB internal storage variant in this budget. Its 6.56-inch HDR10+ compliant Full HD+ AMOLED display has 120Hz refresh rate and can display a billion colour shades. The phone launched with Android 12 with FunTouch OS 12, and the company released an Android 13 update for the phone a few months ago. One can expect more software updates for this device in the future.

iQOO-9-1

The rear camera department here is quite versatile too. You get a 48MP primary camera with Gimbal stabilisation, accompanied by a 13MP ultra-wide camera and a 13MP 50 mm professional portrait camera for great portrait shots. The 16MP front camera is more than handy for selfies and video calls. The iQOO 9 5G has a 4350 mAh battery that can last over a day of moderate use, and the bundled 120W fast charger claims to charge it fully in just 18 minutes.

iQOO 9 5G price in India: Rs 37,990 for 12GB RAM/256GB storage

Asus ROG Phone 5s
Here is a surprise entrant in this list. A relatively old phone but still highly relevant for mobile gamers, and certainly a very interesting option at this price point. We are talking about the Asus ROG Phone 5s. Other than powerful processing hardware, the phone has several optimisations and enhancements to give gamers an immersive gaming experience. The phone is powered by a Qualcomm Snapdragon 888+ SoC which is still fairly powerful for gaming, and you get 8 GB RAM and 128 GB internal storage to go with it.

Asus ROG Phone 5s

Its large 6.78-inch Full HD+ 10-bit AMOLED display has a 144 Hz refresh rate, HDR10+ compliance and can get up to 1200 nits bright. This phone is targeted primarily at mobile gamers, but it can handle photography reasonably well, courtesy of a 64MP primary camera, 13MP ultra-wide snapper and a 5MP macro camera. The Asus ROG Phone 5s has a large 6000 mAh battery for long gaming sessions, and the bundled 65W fast charger can recharge it briskly. This phone launched with Android 11 and Asus’ ROG UI, and a stable Android 13 update has started rolling out recently.

Asus ROG Phone 5s price in India: Rs 39,999 for 8GB RAM/128GB storage


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Read Now: Blade Runner Show Possibly Delayed a Full Year as Companies Refuse to Pay Writers – 101 Latest News

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Blade Runner Show Possibly Delayed a Full Year as Companies Refuse to Pay Writers

#Blade #Runner #Show #Possibly #Delayed #Full #Year #Companies #Refuse #Pay #Writers

Image: Warner Bros.

You can now add the upcoming Blade Runner 2099 TV show to the list of shows impacted by the Writers Strike.

According to the BBC, the Prime Video series was set to start shooting at Belfast Harbour Studios in Northern Ireland. The ongoing strike by the Writers Guild of America also affects writers whose shows or films are filming outside of the US, such as 2099. And even though it hasn’t even been a full month since the strike started, the sci-fi series may not end up starting up production again until spring 2024.

Speaking to the outlet, Northern Ireland Screen (the country’s national screen agency) said it was “extremely disappointed” by production being halted. Its CEO Richard Williams added that the company “hope a fair deal is reached soon so crew can get back to work.” In the meantime, NI Screen plans to find something else to take up 2099’s production schedule, while being mindful that “many freelance crew and supply chain companies were relying on this project for work in the months ahead.”

Blade Runner 2099 was officially picked up by Prime Video last September as a limited series with original Blade Runner director Ridley Scott on hand as an executive producer. We know that it’s set 50 years after 2017’s Blade Runner 2049, but details on the show have otherwise been basically nonexistent. The biggest piece of recent news was back in March, with Killing Eve’s Jodie Comer reportedly in talks to star.

The news of 2099’s production being halted comes not long after Marvel Studios decided to kill production for both Thunderbolts and Wonder Man for the foreseeable future. Countless other films and shows have stopped production in the month of May as a result of picketing writers, which has to be a blow felt by all the companies as solidarity for the writers grows and the WGA may not be the only ones picketing for better pay and profits from streaming services.


Want more io9 news? Check out when to expect the latest Marvel, Star Wars, and Star Trek releases, what’s next for the DC Universe on film and TV, and everything you need to know about the future of Doctor Who.

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Read Now: Watch this Nvidia demo and imagine actually speaking to AI game characters – 101 Latest News

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Watch this Nvidia demo and imagine actually speaking to AI game characters

#Watch #Nvidia #demo #imagine #speaking #game #characters

Image: Nvidia

At Computex 2023 in Taipei, Nvidia CEO Jensen Huang just gave the world a glimpse of what it might be like when gaming and AI collide — with a graphically breathtaking rendering of a cyberpunk ramen shop where you can actually talk to the proprietor.

Seriously, instead of clicking on dialogue options, it imagines you could hold down a button, just say something with your own voice, and get an answer from a video game character. Nvidia’s calling it a “peek at the future of games.”

Unfortunately, the actual dialogue leaves a lot to be desired — maybe try GPT-4 or Sudowrite next time, Nvidia?

Here’s the entire conversation I hastily transcribed:

Player: Hey Jin, how are you?

Jin: Unfortunately not so good.

How come?

I am worried about…

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